Cholestatic jaundice due to methyldopa.

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Cholestatic jaundice due to methyldopa.

The occurrence of hepatitis in patients taking methyldopa was first described over 10 years ago (Gillespie et al., 1962). Though the degree of bile retention in puiblished case reports varies considerably (Tysell and Knauer, 1971) the clinical picture described is generally indistinguishable from viral hepatitis. When the following patient was seen drug-induced jaundice was suspected but as we ...

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Cholestatic jaundice due to toxoplasma hepatitis.

Introduction Acquired toxoplasmosis may present as acute hepatitis (Vischer, Bernheim and Engelbrecht, 1967; Weitberg et al., 1979; Bars et al., 1978; Kouba, Jira and Zitova, 1971). Bars et al. (1978) in a survey of the literature reported 11 such cases. Weitberg et al. (1979) reported a case of granulomatous hepatitis due to Toxoplasma gondii and suggested that the severity of hepatitis may be...

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Cholestatic jaundice due to co-trimoxazole.

A patient developed cholestatic jaundice following therapy with co-trimoxazole. Inadvertent re-challenge with the drug resulted in further clinical and biochemical deterioration, but complete recovery ensued on stopping this drug.

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Familial Intrahepatic Cholestatic Jaundice

Recurrent jaundice due to intrahepatic cholestasis is reported most often in adults. Some varieties are familial and are associated with failure of excretion of conjugated bilirubin by the liver cell. The original descriptions of these types given by Rotor, Manahan, and Florentin (1948) and Dubin and Johnson (1954) concerned patients with a benign recurrent jaundice. The diseases described by t...

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Cephalexin Induced Cholestatic Jaundice

Cephalexin is a very commonly prescribed orally administered antibiotic which has many potential side effects. Amongst these cholestatic jaundice has been infrequently reported as an adverse reaction. We present a case of a 57-year-old male who exhibited features of cholestatic jaundice including elevated liver function tests (LFTs) after taking cephalexin and showed improvement on removal of t...

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ژورنال

عنوان ژورنال: BMJ

سال: 1974

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.3.5930.559